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Basic Immunology - Definitions

How the immune system works:

  • helps to protect against infection
  • identifies and removes germs
  • germs are either bacteria or viruses
  • produces antibodies and white blood cells which attack the germs
  • has a very strong memory ('immune memory') that enables it to recognize foreign substances that it has seen years before
  • this allows the body to fight germs

How immunization works:

  • exposing the immune system to vaccines which contain germs or parts of germs causes the immune system to respond just like it does for infection
  • the body makes the same antibodies it would in response to infection
  • immunization triggers immune memory without the risk of illness or death associated with infection. The body can fight off the specific germ if an exposure occurs
  • vaccines like all medicines must go through a series of steps before their use is approved for the public
  • vaccine safety is taken very seriously by health authorities in Canada, including the provincial and federal governments and the Canadian Paediatric Society
  • before a vaccine is approved for use it must be shown to be safe and effective in preventing the disease for which it is intended.

DEFINITIONS

Bacteria

  • microscopic organisms that are able to live on their own provided they have essential chemicals to nourish them

Viruses

  • microscopic organisms that are unable to live on their own
  • to grow and reproduce, viruses must get inside of cells

Antigens

  • bacteria and viruses have unique proteins and complex sugars on their surface called antigens
  • antigens enable the germ to stick to human cells
  • the immune system targets bacterial and viral antigens

White blood cells

  • special blood cells (T-cells) help the immune system kill germs along with antibodies

Immune system

  • a system in your body that helps to recognize and fight infection and foreign substances in the body

Immune memory

  • the immune system has a strong memory that enables it to recognize foreign substances that enter the body even if the exposure occurred many years before
  • immune memory is particular to specific germs and it does not mean that immune memory has been developed for all types of germs

Incubation period

  • the time between when a person is infected with a bacteria or virus and the onset of symptoms. This varies for each germ.

Chronic carriers

  • persons who carry a virus in their blood but do not have any symptoms of illness

(Courtesy of Peel Public Health)


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